Third-time lung transplant using extended criteria lungs

Ann Thorac Surg. 2007 Aug;84(2):642-4. doi: 10.1016/j.athoracsur.2007.03.023.

Abstract

There is an increasing requirement for lung re-transplants (re-LTx) related to the bronchiolitis obliterans syndrome. Nevertheless, re-LTx, especially second-time re-LTx, poses the dilemma of appropriate allocation of a scarce donor lung resource versus the desire to optimize outcomes for an individual patient. Extended donors have been used to partially alleviate a scarce donor lung supply with satisfactory outcomes for primary lung transplant. However, the usefulness of the extended donors remains unknown, including donation-after-cardiac-death donors for re-LTx. This report describes a second-time re-LTx using significantly extended donor criteria lungs from a Maastricht category IV donation-after-cardiac-death donor with resultant good clinical outcomes.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Brain Death
  • Humans
  • Lung Transplantation / methods*
  • Male
  • Mycoses / prevention & control
  • Patient Selection
  • Postoperative Complications / prevention & control
  • Pyrimidines / therapeutic use
  • Reoperation*
  • Tissue Donors / statistics & numerical data*
  • Treatment Outcome
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole