Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon

Chem Commun (Camb). 2007 Aug 7:(29):3057-9. doi: 10.1039/b705932a. Epub 2007 Jun 29.

Abstract

In advanced studies directed toward the total synthesis of the kedarcidin chromophore, we have successfully achieved the late-stage installation of the nine-membered diyne ring in the presence of the highly functionalised ansamacrocyclic bridge.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry*
  • Cycloparaffins / chemical synthesis*
  • Cycloparaffins / chemistry
  • Enediynes / chemical synthesis*
  • Enediynes / chemistry
  • Molecular Structure
  • Naphthalenes / chemical synthesis*
  • Naphthalenes / chemistry

Substances

  • Cycloparaffins
  • Enediynes
  • Naphthalenes
  • kedarcidin chromophore
  • Carbon