[Case of advanced gastric cancer successfully treated with chemotherapy of weekly paclitaxel]

Gan To Kagaku Ryoho. 2007 Jul;34(7):1107-9.
[Article in Japanese]

Abstract

We report a case of gastric cancer with ascites treated with chemotherapy. The patient is a 67-year-old male. Combination chemotherapy of S-1 and CDDP was given as the first-line treatment. However, the symptoms did not improve with that regimen, so we decided to change the chemotherapy to paclitaxel as second-line treatment. After 4 cycles, CT scan revealed decreasing ascites and endoscopy a reduction of the primary tumor. The patient has maintained a condition of decreasing ascites with improvement of QOL for 8 months. This regimen is considered effective treatment for unresectable gastric cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / secondary
  • Aged
  • Antineoplastic Agents, Phytogenic / administration & dosage*
  • Cisplatin
  • Drug Administration Schedule
  • Drug Combinations
  • Drug Resistance, Neoplasm
  • Humans
  • Infusions, Intravenous
  • Male
  • Oxonic Acid
  • Paclitaxel / administration & dosage*
  • Peritoneal Neoplasms / drug therapy
  • Peritoneal Neoplasms / secondary
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology
  • Tegafur

Substances

  • Antineoplastic Agents, Phytogenic
  • Drug Combinations
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid
  • Paclitaxel
  • Cisplatin