Impact of the COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5, on clinical laboratory operations

Jeffrey J Germer; Jordan L Bendel; Craig A Dolenc; Sarah R Nelson; Amanda L Masters; Tara M Gerads; Jayawant N Mandrekar; P Shawn Mitchell; Joseph D C Yao

doi:10.1128/JCM.00656-07

Impact of the COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5, on clinical laboratory operations

J Clin Microbiol. 2007 Sep;45(9):3101-4. doi: 10.1128/JCM.00656-07. Epub 2007 Jul 18.

Authors

Jeffrey J Germer¹, Jordan L Bendel, Craig A Dolenc, Sarah R Nelson, Amanda L Masters, Tara M Gerads, Jayawant N Mandrekar, P Shawn Mitchell, Joseph D C Yao

Affiliation

¹ Division of Clinical Microbiology, Mayo Clinic, Su 1-602, 200 First Street SW, Rochester, MN 55905, USA.

Abstract

The COBAS AmpliPrep/COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5 (CAP/CA), and the COBAS AMPLICOR HIV-1 MONITOR Test, version 1.5, were compared. CAP/CA reduced and consolidated labor while modestly increasing assay throughput without increased failure rates or direct costs, regardless of batch size and assay format.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

HIV Infections / diagnosis*
HIV Infections / virology*
HIV-1 / genetics
HIV-1 / isolation & purification*
Humans
Molecular Diagnostic Techniques / economics
Molecular Diagnostic Techniques / methods*
Sensitivity and Specificity
Virology / economics
Virology / methods*