Efficient synthesis of salicylates by catalytic [3 + 3] cyclizations of 1,3-bis(silyl enol ethers) with 1,1,3,3-tetramethoxypropane

J Org Chem. 2007 Aug 3;72(16):6284-6. doi: 10.1021/jo070974a. Epub 2007 Jul 13.

Abstract

Salicylic acid derivatives were prepared by Me3SiOTf-catalyzed [3 + 3] cyclization of 1,3-bis(silyl enol ethers) with 1,1,3,3-tetramethoxypropane.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Chemistry, Organic / methods*
  • Cyclization
  • Ethers / chemistry*
  • Ethyl Ethers / chemistry
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Models, Chemical
  • Propane / analogs & derivatives*
  • Propane / chemistry
  • Salicylates / chemical synthesis*
  • Salicylates / chemistry
  • Salicylic Acid / chemistry

Substances

  • Ethers
  • Ethyl Ethers
  • Salicylates
  • 1,1,3,3-tetramethoxypropane
  • Salicylic Acid
  • Propane