Does laryngopharyngeal reflux affect healing and recovery after tonsillectomy?

J Laryngol Otol. 2008 Jun;122(6):603-8. doi: 10.1017/S0022215107009760. Epub 2007 Jul 11.

Abstract

Introduction: Laryngopharyngeal reflux is increasingly being implicated in several otolaryngological disorders.

Aims: To study a potential correlation between pre-operative laryngopharyngeal reflux and wound healing and recovery after tonsillectomy, based on subjective and objective findings.

Materials and methods: A prospective, blinded study was undertaken, including 60 patients scheduled for tonsillectomy, divided into two equal groups: a study group (group A) with pre-operative laryngopharyngeal reflux documented using ambulatory 24-hour pH monitoring; and a control group (group B) without laryngopharyngeal reflux.

Results: Group A had significantly higher pain scores on the seventh and 14th post-operative days (p = 0.022 and p = 0.000, respectively) and took a significantly longer time to return to normal eating (p = 0.013), compared with group B. Group A also showed significantly slower healing on the seventh and 14th post-operative days, as estimated by assessing the grade of post-operative slough formation (p = 0.016 and p = 0.029, respectively). A significant correlation between the number of pharyngeal reflux episodes and the degree of post-operative slough was also found.

Conclusions: Laryngopharyngeal reflux can significantly decrease wound healing following tonsillectomy. Therefore, pre-operative recognition and management of this condition is desirable in order to eliminate its negative post-operative effect.

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Female
  • Gastroesophageal Reflux / complications*
  • Humans
  • Male
  • Pain, Postoperative / etiology*
  • Prospective Studies
  • Single-Blind Method
  • Tonsillectomy*
  • Wound Healing*