Contribution of a novel gene, rpeA, encoding a putative autotransporter adhesin to intestinal colonization by rabbit-specific enteropathogenic Escherichia coli

Infect Immun. 2007 Sep;75(9):4664-9. doi: 10.1128/IAI.00972-06. Epub 2007 Jul 9.

Abstract

Rabbit-specific enteropathogenic Escherichia coli (REPEC) is an attaching and effacing pathogen of young rabbits. Using signature-tagged mutagenesis, we identified several known colonization factors of REPEC as well as a gene predicted to encode a novel autotransporter protein. This novel gene was termed rpeA for REPEC plasmid-encoded autotransporter.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesins, Bacterial / genetics*
  • Adhesins, Bacterial / physiology
  • Adhesins, Escherichia coli / genetics*
  • Adhesins, Escherichia coli / physiology
  • Animals
  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Escherichia coli / growth & development
  • Escherichia coli / pathogenicity
  • Escherichia coli Proteins / genetics*
  • Escherichia coli Proteins / physiology
  • Fimbriae Proteins / genetics*
  • HeLa Cells
  • Humans
  • Intestinal Mucosa / enzymology
  • Intestinal Mucosa / microbiology*
  • Molecular Sequence Data
  • Rabbits

Substances

  • Adhesins, Bacterial
  • Adhesins, Escherichia coli
  • Escherichia coli Proteins
  • RpeA protein, E coli
  • colonization factor antigens
  • Fimbriae Proteins

Associated data

  • GENBANK/AY552473