Histopathological study of porcine gastric mucosa with and without a spiral bacterium ("Gastrospirillum suis")

J Med Microbiol. 1991 Dec;35(6):345-8. doi: 10.1099/00222615-35-6-345.

Abstract

Tightly spiralled bacteria ("Gastrospirillum suis") were seen in the pyloric mucosa of the stomach of 13 (10.8%) of 120 pigs that appeared clinically healthy at slaughter and in the fundic mucosa of three (5.0%) out of 60 pigs. The spiral organism could not be cultured from any pig. Chronic gastritis was observed in the pyloric mucosa of 53 (44.2%) of 120 pigs and in the fundic mucosa of 7 (11.7%) of 60 pigs. The 13 pigs with spiral bacteria in the pyloric region comprised one animal (7.7%) with normal pyloric mucosa, two (15.4%) with "borderline gastritis", and 10 (76.9%) with chronic gastritis--in one instance accompanied by signs of activity (numerous polymorphonuclear cells). The three pigs with spiral bacteria in the fundic mucosa comprised two animals with a normal fundic region and one with "borderline gastritis". The presence of the spiral bacterium was significantly associated with pyloric gastritis (p = 0.013) and with numbers of lymphoid follicles (p = 0.014).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chronic Disease
  • Female
  • Gastric Fundus / microbiology
  • Gastric Fundus / pathology
  • Gastric Mucosa / microbiology*
  • Gastric Mucosa / pathology
  • Gastritis / microbiology
  • Gastritis / pathology
  • Gastritis / veterinary
  • Helicobacter pylori / growth & development
  • Helicobacter pylori / isolation & purification*
  • Male
  • Pylorus / microbiology
  • Pylorus / pathology
  • Swine
  • Swine Diseases / microbiology
  • Swine Diseases / pathology