Oral Candida and Enterobacteriaceae in HIV-1 infection: correlation with clinical candidiasis and antimycotic therapy

Abstract

Oral swabs of 73 HIV-1 infected men (32 under conditions of antimycotic treatment (43.8%)) and 58 controls were cultured for Candida species and Enterobacteriaceae. In Group A without antimycotics, yeasts were isolated from 35/41 swabs (85.4%) (range 2 x 10(1) - 4 x 10(6) cfu/ml). In Group B with antimycotics, yeasts were cultured from 27/32 swabs (84.4%) (4 x 10(1) - 1 x 10(6) cfu/ml). Oral Enterobacteriaceae (o.e.) were grown from 22% of the swabs of both Group A (2 x 10(1) - 2 x 10(6) cfu/ml) and Group B (4 x 10(1) - 1.6 x 10(6) cfu/ml). Growth of o.e. and yeasts (2 x 10(3) - 4 x 10(6) cfu/ml). Correlation between yeasts and o.e. were isolated in 14% (2 x 10(1) - 6.4 x 10(6) cfu/ml). Correlation between yeasts species to local and systemic treatment deserves further investigations.