Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease

Circulation. 2007 May 15;115(19):2540-8. doi: 10.1161/CIRCULATIONAHA.107.670588.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adipose Tissue, Brown / metabolism
  • Animals
  • Cardiomegaly / metabolism
  • Cardiomegaly / physiopathology
  • Cardiomyopathies / metabolism
  • Cardiomyopathies / physiopathology*
  • DNA, Mitochondrial / genetics
  • ERRalpha Estrogen-Related Receptor
  • Energy Metabolism / physiology
  • Fatty Acids / metabolism
  • Gene Expression Regulation / physiology
  • Glucose / metabolism
  • Heart Failure / metabolism
  • Heart Failure / physiopathology
  • Heat-Shock Proteins / physiology*
  • Humans
  • Mice
  • Mice, Knockout
  • Mitochondria, Heart / metabolism
  • Mitochondria, Heart / physiology*
  • Models, Animal
  • Models, Biological
  • Nuclear Respiratory Factor 1 / physiology
  • Oxidation-Reduction
  • Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
  • Peroxisome Proliferator-Activated Receptors / physiology
  • Receptors, Estrogen / physiology
  • Trans-Activators / physiology*
  • Transcription Factors / physiology*
  • Transcription, Genetic

Substances

  • DNA, Mitochondrial
  • Fatty Acids
  • Heat-Shock Proteins
  • NRF1 protein, human
  • Nrf1 protein, mouse
  • Nuclear Respiratory Factor 1
  • PPARGC1A protein, human
  • Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
  • Peroxisome Proliferator-Activated Receptors
  • Ppargc1a protein, mouse
  • Receptors, Estrogen
  • Trans-Activators
  • Transcription Factors
  • Glucose