Alteration of beta-secretase traffic by the receptor tyrosine kinase signaling pathway - a new mechanism for regulating Alzheimer's beta-amyloid production

Cell Res. 2007 May;17(5):385-6. doi: 10.1038/cr.2007.41.
No abstract available

Publication types

  • Comment

MeSH terms

  • Alzheimer Disease / physiopathology
  • Amyloid Precursor Protein Secretases / metabolism*
  • Amyloid beta-Peptides / biosynthesis*
  • Animals
  • Aspartic Acid Endopeptidases / metabolism*
  • Enzyme Activation
  • Epidermal Growth Factor / physiology
  • Humans
  • Mice
  • Nerve Growth Factor / physiology
  • Receptor Protein-Tyrosine Kinases / physiology*
  • Signal Transduction / physiology*
  • trans-Golgi Network / physiology

Substances

  • Amyloid beta-Peptides
  • Epidermal Growth Factor
  • Nerve Growth Factor
  • Receptor Protein-Tyrosine Kinases
  • Amyloid Precursor Protein Secretases
  • Aspartic Acid Endopeptidases
  • Bace1 protein, mouse