Treatment of steroid-resistant acute GVHD with OKT3 and high-dose steroids results in better disease control and lower incidence of infectious complications when compared to high-dose steroids alone: a randomized multicenter trial by the EBMT Chronic Leukemia Working Party

Leukemia. 2007 Aug;21(8):1830-3. doi: 10.1038/sj.leu.2404731. Epub 2007 May 10.
No abstract available

Publication types

  • Letter
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Bacterial Infections / immunology
  • Bacterial Infections / microbiology
  • Bacterial Infections / therapy
  • Bone Marrow Transplantation*
  • CD3 Complex / analysis
  • Female
  • Graft Rejection / drug therapy*
  • Graft Rejection / immunology
  • Graft Rejection / microbiology
  • Graft vs Host Disease / microbiology
  • Graft vs Host Disease / therapy*
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Incidence
  • Leukemia / complications
  • Leukemia / therapy
  • Lymphoma / complications
  • Lymphoma / therapy
  • Male
  • Middle Aged
  • Muromonab-CD3 / therapeutic use*
  • Peripheral Blood Stem Cell Transplantation*
  • Prospective Studies
  • Remission Induction
  • Steroids / therapeutic use*

Substances

  • CD3 Complex
  • Immunosuppressive Agents
  • Muromonab-CD3
  • Steroids