Prevalence of glaucoma in patients with obstructive sleep apnoea--a cross-sectional case-series

Eye (Lond). 2008 Sep;22(9):1105-9. doi: 10.1038/sj.eye.6702846. Epub 2007 May 4.

Abstract

Aim: To determine the prevalence of glaucoma in patients with obstructive sleep apnoea.

Design: Cross-sectional case series.

Participants: One hundred patients with moderate to severe obstructive sleep apnoea.

Testing: Within 48 h of the polysomnographic diagnosis of obstructive sleep apnoea, patients underwent the following tests: intraocular pressure, gonioscopy, automated perimetry, stereoscopic biomicroscopy, and fundascopic assessment for the presence of glaucomatous optic nerve changes.

Main outcome measures: The prevalence of glaucoma in patients with obstructive sleep apnoea and the associations between patient characteristics and both glaucoma and intraocular pressure.

Results: Glaucoma was diagnosed in 27 of 100 patients yielding an estimated prevalence of 27% (95% CI 19-37%). The presence of glaucoma did not correlate with sex, body mass index (BMI), or AHI, but did appear to be associated with age (P=0.014). There was no evidence of a relationship between intraocular pressure and either the apnoea plus hypopnoea index or age.

Conclusion: The prevalence of glaucoma in patients with obstructive sleep apnoea is an estimated 27%. Sex, age, body mass index or apnoea plus hypopnoea index are not factors influencing the presence of glaucoma in this population of patients.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Female
  • Glaucoma / complications*
  • Glaucoma / epidemiology
  • Humans
  • Intraocular Pressure / physiology*
  • Male
  • Middle Aged
  • Polysomnography
  • Prevalence
  • Risk Factors
  • Sleep Apnea, Obstructive / epidemiology
  • Sleep Apnea, Obstructive / etiology*
  • United States / epidemiology
  • Visual Acuity / physiology*
  • Visual Field Tests