Dinuclear ruthenium(II) triple-stranded helicates: luminescent supramolecular cylinders that bind and coil DNA and exhibit activity against cancer cell lines

Angew Chem Int Ed Engl. 2007;46(23):4374-8. doi: 10.1002/anie.200700656.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • Binding Sites
  • Cell Line, Tumor
  • Crystallography, X-Ray
  • DNA / chemistry*
  • DNA / drug effects
  • Drug Screening Assays, Antitumor
  • Humans
  • Ligands
  • Luminescence
  • Macromolecular Substances / chemistry
  • Macromolecular Substances / isolation & purification
  • Macromolecular Substances / pharmacology
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Organometallic Compounds / isolation & purification
  • Organometallic Compounds / pharmacology
  • Ruthenium / chemistry*
  • Structure-Activity Relationship

Substances

  • Antineoplastic Agents
  • Ligands
  • Macromolecular Substances
  • Organometallic Compounds
  • Ruthenium
  • DNA