Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors

Angew Chem Int Ed Engl. 2007;46(22):4115-9. doi: 10.1002/anie.200604825.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Colorimetry
  • Disaccharides / antagonists & inhibitors
  • Disaccharides / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Hydrogen Bonding
  • Inositol / analogs & derivatives
  • Inositol / antagonists & inhibitors
  • Inositol / chemistry
  • Protein Conformation
  • Trehalase / antagonists & inhibitors*
  • Trehalase / chemistry*

Substances

  • Disaccharides
  • Enzyme Inhibitors
  • trehazolin
  • validamycin A
  • Inositol
  • Trehalase