Recombinant follicle-stimulating hormone (rFSH) supplemented with low-dose human chorionic gonadotropin compared with rFSH alone for ovarian stimulation for in vitro fertilization

Anne K Van Horne; G Wright Bates Jr; Randal D Robinson; Nancy J Arthur; Anthony M Propst

doi:10.1016/j.fertnstert.2006.12.051

Recombinant follicle-stimulating hormone (rFSH) supplemented with low-dose human chorionic gonadotropin compared with rFSH alone for ovarian stimulation for in vitro fertilization

Fertil Steril. 2007 Oct;88(4):1010-3. doi: 10.1016/j.fertnstert.2006.12.051. Epub 2007 Apr 16.

Authors

Anne K Van Horne¹, G Wright Bates Jr, Randal D Robinson, Nancy J Arthur, Anthony M Propst

Affiliation

¹ Division of Reproductive Endocrinology and Infertility, San Antonio Uniformed Services Health Education Consortium, Wilford Hall Medical Center, Lackland Air Force Base, Texas, USA.

PMID: 17434503
DOI: 10.1016/j.fertnstert.2006.12.051

Abstract

Low-dose hCG supplementation was administered at the start of ovarian stimulation, concomitantly with recombinant FSH (rFSH) in GnRH antagonist cycles, and these were compared with GnRH-a cycles that used rFSH alone. The low-dose hCG group had similar implantation and pregnancy rates but had significantly reduced rFSH requirements, allowing for an average cost savings of $600 per cycle.

MeSH terms

Adult
Chorionic Gonadotropin / administration & dosage*
Female
Fertilization in Vitro / methods*
Follicle Stimulating Hormone / administration & dosage*
Gonadotropin-Releasing Hormone / administration & dosage
Gonadotropin-Releasing Hormone / analogs & derivatives
Humans
Ovulation Induction / methods*
Pregnancy
Pregnancy Rate
Recombinant Proteins / administration & dosage
Retrospective Studies

Substances

Chorionic Gonadotropin
Recombinant Proteins
Gonadotropin-Releasing Hormone
Follicle Stimulating Hormone
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