[Studies on chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang]

Zhongguo Zhong Yao Za Zhi. 2007 Feb;32(3):235-7.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang.

Method: To isolated the compounds by silica gel and sephadex LH -20 column chromatography and their structures were elucidate by means of spectral analysis.

Result: Six sterols, one fatty acid and one of diketopiperazines were obtained from CHCl3 fraction of EtOH extract and identified as ergosta-7, 22-dien-3beta-ol (1), ergosterol (2), 6, 9-epidioxyergosta-7, 22-dien-3beta-ol (3), 5, 8-epidioxiergosta-6, 22-dien-3beta-ol (4), ergosta-7, 22-dien-3-one (5), beta-sitosterol (6), alpha-Hydroxytetracosanoic acid (7), cyclo (D-Pro-D-Val) (8).

Conclusion: Componds 1-8 are isolated from G. sinense Zhao, Xu et Zhang for the first time.

MeSH terms

  • Chromatography, Gel / methods
  • Ergosterol / analogs & derivatives*
  • Ergosterol / chemistry
  • Ergosterol / isolation & purification*
  • Fruiting Bodies, Fungal / chemistry*
  • Ganoderma / chemistry*
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification
  • Spectrum Analysis / methods

Substances

  • Sitosterols
  • ergosta-7,22-dien-3-one
  • gamma-sitosterol
  • Ergosterol