Value of dynamic enhanced magnetic resonance imaging for distinguishing between ovarian fibroma and subserous uterine leiomyoma

J Comput Assist Tomogr. 2007 Mar-Apr;31(2):236-42. doi: 10.1097/01.rct.0000237810.88251.9e.

Abstract

Purpose: The purpose of this study was to assess the accuracy of magnetic resonance imaging (MRI), particularly, dynamic MRI, in distinguishing ovarian fibromas from subserous uterine leiomyomas.

Material and methods: Fifteen ovarian fibromas and 15 subserous uterine leiomyomas were retrospectively reviewed. All MR examinations included dynamic contrast-enhanced (DCE) sequences. Morphological criteria (size, T1 and T2 signals, ovarian tissue, associated uterine leiomyoma, and pelvic fluid), arterial vessels, time-intensity curves (maximal enhancement and signal intensity at 30, 60, and 90 seconds), and signal intensity on delayed T1-weighted images were compared between the 2 groups.

Results: No significant difference in morphological criteria was noted between the 2 types of masses. Visualization of arterial vessels was more frequent in uterine leiomyomas than in ovarian fibromas (P= 0.002). The DCE MR enhancement rate was higher for uterine leiomyomas than for ovarian fibromas in terms of both maximal enhancement (P < 0.001) and enhancement rate at 30 (P = 0.009), 60 (P = 0.007), and 90 seconds (P = 0.0009). On delayed T1 postcontrast sequence, no statistical difference exists between signal intensity of ovarian fibromas and uterine leiomyomas.

Conclusion: Our findings suggest that DCE MRI can distinguish ovarian fibromas from uterine leiomyomas and should be used if sonography fails to show the origin of a pelvic mass.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Contrast Media / administration & dosage
  • Diagnosis, Differential
  • Female
  • Fibroma / diagnosis*
  • Humans
  • Image Enhancement / methods*
  • Leiomyoma / diagnosis*
  • Longitudinal Studies
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Observer Variation
  • Ovarian Neoplasms / diagnosis*
  • Predictive Value of Tests
  • Reproducibility of Results
  • Retrospective Studies
  • Uterine Neoplasms / diagnosis*

Substances

  • Contrast Media