Complex dynamics in a cross-catalytic self-replication mechanism

Kathleen M Beutel; Enrique Peacock-López

doi:10.1063/1.2716396

Complex dynamics in a cross-catalytic self-replication mechanism

J Chem Phys. 2007 Mar 28;126(12):125104. doi: 10.1063/1.2716396.

Authors

Kathleen M Beutel¹, Enrique Peacock-López

Affiliation

¹ Department of Chemistry, Williams College, Williamstown, Massachusetts 01267, USA.

PMID: 17411166
DOI: 10.1063/1.2716396

Abstract

The authors consider a minimal cross-catalytic self-replicating system of only two cross-catalytic templates that mimics the R3C ligase ribozyme system of Dong-Eu and Joyce [Chem. Biol. 11, 1505 (2004)]. This system displays considerably more complex dynamics than its self-replicating counterpart. In particular, the authors discuss the Poincare-Andronov-Hopf bifurcation, canard transitions, excitability, and hysteresis that yield birhythmicity between simple and complex oscillations.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Catalysis
Models, Biological*
Polynucleotide Ligases / chemistry*
Polynucleotide Ligases / physiology*
RNA, Catalytic / chemistry*
RNA, Catalytic / physiology*

Substances

RNA, Catalytic
Polynucleotide Ligases
R3C ligase