Serotype distribution and antimicrobial susceptibilities of nasopharyngeal isolates of Streptococcus pneumoniae from children hospitalized for acute respiratory illnesses in Hong Kong

J Clin Microbiol. 2007 Jun;45(6):1969-71. doi: 10.1128/JCM.00620-07. Epub 2007 Apr 4.

Abstract

Five hundred nineteen Streptococcus pneumoniae isolates from nasopharyngeal aspirates of 3,157 children (age, <16 years) participating in a respiratory surveillance study in Hong Kong in 2005 and 2006 indicated that 64.9% and 37.2% of the isolates were not susceptible to penicillin and cefotaxime, respectively. The rate of potential coverage by the seven-valent conjugate vaccine was 72.3%, and the rate increased to 74.6% for serogroup-specific types.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adolescent
  • Anti-Bacterial Agents / pharmacology*
  • Child
  • Child, Preschool
  • Drug Resistance, Bacterial
  • Hong Kong / epidemiology
  • Hospitalization*
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Nasopharynx / microbiology*
  • Pneumococcal Infections / epidemiology*
  • Pneumococcal Infections / microbiology
  • Population Surveillance
  • Respiratory Tract Infections / epidemiology*
  • Respiratory Tract Infections / microbiology
  • Serotyping
  • Streptococcus pneumoniae / classification*
  • Streptococcus pneumoniae / drug effects*
  • Streptococcus pneumoniae / isolation & purification

Substances

  • Anti-Bacterial Agents