Unique monoterpenoid indole alkaloids from Alstonia scholaris

Org Lett. 2007 Apr 26;9(9):1817-20. doi: 10.1021/ol0705301. Epub 2007 Mar 29.

Abstract

[structure: see text] A pair of geometrically isomeric monoterpenoid indole alkaloids with a skeleton rearrangement and two additional carbons, named (19,20) E-alstoscholarine (1) and (19,20) Z-alstoscholarine (2), were obtained from the leaf extract of Alstonia scholaris. Their structures were elucidated on the basis of spectroscopic methods and then confirmed by X-ray crystal diffraction. The biogenesis of these compounds was also proposed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alstonia / chemistry*
  • Alstonia / metabolism
  • Crystallography, X-Ray
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Molecular Structure
  • Secologanin Tryptamine Alkaloids / chemistry*
  • Secologanin Tryptamine Alkaloids / metabolism

Substances

  • Secologanin Tryptamine Alkaloids