miRNA editing--we should have inosine this coming

Mol Cell. 2007 Mar 23;25(6):792-3. doi: 10.1016/j.molcel.2007.03.010.

Abstract

In a recent issue of Science, Nishikura and colleagues provide the first evidence that editing of a microRNA (miRNA) precursor by ADARs can modulate the target specificity of the mature miRNA (Kawahara et al., 2007).

Publication types

  • Comment

MeSH terms

  • Animals
  • Humans
  • Inosine / metabolism*
  • Introns
  • MicroRNAs / genetics*
  • RNA Editing / genetics*
  • RNA Interference*
  • RNA, Double-Stranded / metabolism
  • RNA, Small Interfering / genetics

Substances

  • MicroRNAs
  • RNA, Double-Stranded
  • RNA, Small Interfering
  • Inosine