Effect of Alchemilla vulgaris extract on the structure and function of erythrocyte membranes during experimental arterial hypertension

M B Plotnikov; O I Aliev; V Yu Andreeva; A S Vasil'ev; G I Kalinkina

doi:10.1007/s10517-006-0259-0

Effect of Alchemilla vulgaris extract on the structure and function of erythrocyte membranes during experimental arterial hypertension

Bull Exp Biol Med. 2006 Jun;141(6):708-11. doi: 10.1007/s10517-006-0259-0.

[Article in English, Russian]

Authors

M B Plotnikov¹, O I Aliev, V Yu Andreeva, A S Vasil'ev, G I Kalinkina

Affiliation

¹ Laboratory for Pharmacology of Blood Circulation, Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.

PMID: 17364056
DOI: 10.1007/s10517-006-0259-0

Abstract

The course of treatment with Alchemilla vulgaris extract increased the concentrations of lipids and phospholipids in erythrocyte membranes, decreased the number of abnormal erythrocytes, and improved deformability of red blood cells in rats with arterial hypertension.

Publication types

Comparative Study

MeSH terms

Alchemilla / chemistry*
Animals
Densitometry
Erythrocyte Membrane / drug effects*
Erythrocyte Membrane / metabolism
Erythrocytes / drug effects*
Erythrocytes / ultrastructure
Hypertension / blood*
Hypertension / drug therapy
Male
Microscopy, Electron
Phospholipids / metabolism
Plant Extracts / pharmacology
Plant Extracts / therapeutic use
Rats
Rats, Inbred SHR
Rats, Wistar

Substances

Phospholipids
Plant Extracts