Simultaneous ST-segment elevation in the right precordial and inferior leads in Brugada syndrome

J Cardiovasc Med (Hagerstown). 2007 Mar;8(3):201-4. doi: 10.2459/01.JCM.0000260822.29843.c9.

Abstract

We report the case of a patient with genetically confirmed Brugada syndrome who presented with ST-segment elevation in the right precordial and inferior leads. The presenting arrhythmia was atrial fibrillation, which degenerated into ventricular fibrillation during intravenous amiodarone. A flecainide test was markedly positive. Four appropriate cardioverter-defibrillator discharges occurred during a two-year follow-up period after implantation of the device.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atrial Fibrillation / etiology
  • Atrial Fibrillation / physiopathology*
  • Atrial Fibrillation / therapy
  • Brugada Syndrome / complications
  • Brugada Syndrome / genetics
  • Brugada Syndrome / physiopathology*
  • Codon, Nonsense / genetics
  • Defibrillators, Implantable
  • Electrocardiography
  • Heart Conduction System / physiopathology*
  • Humans
  • Male
  • Muscle Proteins / genetics
  • NAV1.5 Voltage-Gated Sodium Channel
  • Sodium Channels / genetics
  • Ventricular Fibrillation / etiology
  • Ventricular Fibrillation / physiopathology
  • Ventricular Fibrillation / therapy

Substances

  • Codon, Nonsense
  • Muscle Proteins
  • NAV1.5 Voltage-Gated Sodium Channel
  • SCN5A protein, human
  • Sodium Channels