Periventricular leukomalacia and prenatal methamphetamine exposure: a case report

Am J Perinatol. 2007 Feb;24(2):123-6. doi: 10.1055/s-2007-970079. Epub 2007 Feb 15.

Abstract

Periventricular leukomalacia (PVL) is a complication of prematurity that carries a high risk of long-term neurologic morbidity. We report the first case, to our knowledge, of unexpected PVL associated with in utero methamphetamine exposure in a 30-week gestation premature infant with a benign hospital course, who subsequently developed cerebral palsy by 24 months of life.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Cerebral Palsy / epidemiology
  • Echoencephalography
  • Female
  • Humans
  • Infant, Newborn
  • Leukomalacia, Periventricular / chemically induced*
  • Leukomalacia, Periventricular / diagnostic imaging
  • Leukomalacia, Periventricular / epidemiology
  • Male
  • Methamphetamine / adverse effects*
  • Pregnancy
  • Prenatal Exposure Delayed Effects*

Substances

  • Methamphetamine