Fusion of FIP1L1 and RARA as a result of a novel t(4;17)(q12;q21) in a case of juvenile myelomonocytic leukemia

Leukemia. 2007 May;21(5):1104-8. doi: 10.1038/sj.leu.2404596. Epub 2007 Feb 15.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Chromosomes, Human, Pair 17*
  • Chromosomes, Human, Pair 4*
  • Dimerization
  • Gene Fusion*
  • Humans
  • Infant
  • Leukemia, Myelomonocytic, Chronic / genetics*
  • Male
  • Oncogene Proteins, Fusion / chemistry
  • Receptor, Platelet-Derived Growth Factor alpha / chemistry
  • Receptors, Retinoic Acid / genetics*
  • Retinoic Acid Receptor alpha
  • Translocation, Genetic*
  • mRNA Cleavage and Polyadenylation Factors / chemistry
  • mRNA Cleavage and Polyadenylation Factors / genetics*

Substances

  • FIP1L1 protein, human
  • Oncogene Proteins, Fusion
  • RARA protein, human
  • Receptors, Retinoic Acid
  • Retinoic Acid Receptor alpha
  • mRNA Cleavage and Polyadenylation Factors
  • FIP1L1-PDGFRA fusion protein, human
  • Receptor, Platelet-Derived Growth Factor alpha