Cell Lysis in SWLA-2 Hybridomas due to 1 kHz AC Electric Fields

Barbara Oakley; Darrin Hanna; Sachin Kandlikar; Brooks Gross; Gabrielle Stryker

doi:10.1109/IEMBS.2005.1616656

Cell Lysis in SWLA-2 Hybridomas due to 1 kHz AC Electric Fields

Conf Proc IEEE Eng Med Biol Soc. 2005:2005:1268-9. doi: 10.1109/IEMBS.2005.1616656.

Authors

Barbara Oakley¹, Darrin Hanna, Sachin Kandlikar, Brooks Gross, Gabrielle Stryker

Affiliation

¹ Sch. of Eng. & Comput. Sci., Oakland Univ., Rochester, MI.

PMID: 17282425
DOI: 10.1109/IEMBS.2005.1616656

Abstract

This paper describes results involving the percentage cell lysis of SWLA-2 murine hybridomas produced by AC electric field pulses at 1 kHz with pulse widths ranging from 1 ms to 1 second. Cells that had been exposed to the electric fields were cultured and replicate samples were examined at 48 hours to determine the number of viable cells.