Discontinuation of secondary prophylaxis against penicilliosis marneffei in AIDS patients after HAART

AIDS. 2007 Jan 30;21(3):365-7. doi: 10.1097/01.aids.0000253374.19966.f9.

Abstract

A retrospective cohort study was conducted to determine the relapse rate of penicilliosis marneffei after the discontinuation of itraconazole secondary prophylaxis in 33 HIV-infected patients who received HAART and had CD4 cell counts of 100 cells/mul or greater for at least 6 months. The observed incidence of relapse of penicilliosis marneffei was zero cases per 641 person-months (95% confidence interval 0-0.6 cases per person-month) after a median follow-up of 18 months (range 6-45).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • AIDS-Related Opportunistic Infections / prevention & control*
  • Acquired Immunodeficiency Syndrome / drug therapy
  • Acquired Immunodeficiency Syndrome / immunology
  • Adult
  • Antifungal Agents / administration & dosage*
  • Antiretroviral Therapy, Highly Active*
  • CD4 Lymphocyte Count
  • Female
  • Follow-Up Studies
  • Humans
  • Itraconazole / administration & dosage
  • Male
  • Middle Aged
  • Mycoses / complications
  • Mycoses / prevention & control*
  • Penicillium / isolation & purification*
  • Recurrence
  • Retrospective Studies

Substances

  • Antifungal Agents
  • Itraconazole