Abstract
A monoclonal antibody (VE8) directed to glycoprotein C of herpes simplex virus type 1 (HSV-1) cross-reacted with all HSV type 2 (HSV-2) strains tested. Positive reaction was also observed with all investigated HSV-1 strains, indicating that the related epitope is consistently present in HSV-1 and HSV-2.
MeSH terms
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Animals
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Antibodies, Monoclonal / immunology
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Cross Reactions
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Epitopes / analysis*
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Immunoblotting
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Mice
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Mice, Inbred BALB C
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Simplexvirus / immunology*
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Viral Envelope Proteins / immunology*
Substances
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Antibodies, Monoclonal
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Epitopes
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Viral Envelope Proteins
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glycoprotein C, herpes simplex virus type 2
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glycoprotein gC, herpes simplex virus type 1