Long-term results and functional outcome after cervical evisceration in patients with thyroid cancer

Surgery. 2006 Dec;140(6):953-9. doi: 10.1016/j.surg.2006.09.001.

Abstract

Background: Surgical strategy in patients with thyroid cancer (TC) infiltrating the aerodigestive system is controversial. This study was undertaken to examine the long-term results of cervical evisceration (CE).

Patients and methods: Since 1995, 14 consecutive patients with advanced TC underwent total laryngectomy (LE, n = 6) or esophagolaryngectomy (ELR, n = 8). Patients with unusual thyroid neoplasms or metastases to the thyroid (n = 3) were excluded. For esophageal reconstruction, free jejunal grafts (n = 6) and gastric tubes (n = 2) were used.

Results: Procedure-related morbidity and mortality were 42% and 14%, respectively. ELR was associated with a significant higher frequency of complications and reoperations compared with LE. Twelve-month and 30-month survival rates were 73% and 55%, respectively; 85% of the patients were satisfied with the surgical results. There were no long-term problems concerning food intake in the ELR patients. Two ELR patients were able to learn a substitutive voice.

Conclusions: Cervical evisceration in patients with TC is associated with significant perioperative morbidity and mortality requiring careful patient selection. Regarding long-term survival, local tumor control, and patient's satisfaction, however, CE should be taken into account in suitable patients with advanced TC.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Disease-Free Survival
  • Esophagectomy* / adverse effects
  • Esophagectomy* / methods
  • Esophagus / pathology*
  • Female
  • Humans
  • Laryngectomy* / adverse effects
  • Laryngectomy* / methods
  • Larynx / pathology*
  • Male
  • Middle Aged
  • Morbidity
  • Neoplasm Invasiveness
  • Prognosis
  • Survival Rate
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / surgery*
  • Time Factors
  • Treatment Outcome