Abstract
Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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DNA / chemistry*
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DNA Breaks, Double-Stranded*
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DNA Cleavage*
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DNA, Bacterial / chemistry
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DNA, Superhelical / chemistry
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Ferrous Compounds / chemical synthesis
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Ferrous Compounds / chemistry*
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Kinetics
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Molecular Structure
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Plasmids / chemistry
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Pyridines / chemical synthesis
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Pyridines / chemistry
Substances
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DNA, Bacterial
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DNA, Superhelical
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Ferrous Compounds
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Pyridines
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DNA