Hole transfer rates in A-form DNA/2'-OMeRNA hybrid

Chemistry. 2007;13(8):2386-91. doi: 10.1002/chem.200601210.

Abstract

The hole transfer rates in the DNA/DNA B-form duplex and DNA/2'-OMeRNA A-form duplex were measured which occurred in the time range of approximately 100 micros. The hole transfer rates in the A-form duplexes were slower and more strongly dependent on the temperature compared to those in the B-form duplexes, suggesting that the A-form is more rigid than the B-form duplex in this time scale.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry*
  • Intercalating Agents
  • Models, Molecular
  • Nuclear Magnetic Resonance, Biomolecular
  • Nucleic Acid Conformation
  • Nucleic Acid Heteroduplexes / chemistry*
  • RNA / chemistry*
  • Stereoisomerism

Substances

  • Intercalating Agents
  • Nucleic Acid Heteroduplexes
  • RNA
  • DNA