[Polyethox corrects hemodynamic and hemorrheological disturbances after infusion-transfusion therapy of massive hemorrhage]

Eksp Klin Farmakol. 2006 Sep-Oct;69(5):27-30.
[Article in Russian]

Abstract

Inclusion of polyethox, a medicinal form of high-molecular (4,5 x 10(6) Da) poly(ethylene oxide), into infusion-transfusion therapy of massive hemorrhage (33% of blood volume) in cats leads to an increase in the stroke and cardiac indices, restores antiturbulent and hemorrheological properties of blood, increases systemic oxygen transport, and reduces hypoxic acid-base balance disturbances.

MeSH terms

  • Acid-Base Equilibrium / drug effects
  • Animals
  • Blood Transfusion
  • Cardiac Volume / drug effects
  • Cats
  • Combined Modality Therapy
  • Female
  • Hemorrhage / drug therapy*
  • Hemorrhage / therapy
  • Male
  • Oxygen / metabolism
  • Polyethylene Glycols / pharmacology
  • Polyethylene Glycols / therapeutic use*
  • Stroke Volume / drug effects

Substances

  • Polyethylene Glycols
  • Oxygen