Recovery of Moraxella ovis from the bovine respiratory tract and differentiation of Moraxella species by tDNA-intergenic spacer PCR

Vet Microbiol. 2007 Mar 10;120(3-4):375-80. doi: 10.1016/j.vetmic.2006.10.037. Epub 2006 Dec 4.

Abstract

The purpose of the present study was to identify Moraxella (M.)--like organisms recovered from calves suffering from respiratory disease down to species level by means of tDNA-intergenic spacer length polymorphism analysis (tDNA-PCR), and to perform antimicrobial susceptibility testing of these isolates using an agar dilution technique. A total of 16 isolates originating from 12 unrelated occasions were identified as Moraxella ovis, and tDNA fingerprinting showed clear delineation from other Moraxella species. The minimal inhibitory concentrations (in microg/mL) for 90% of the investigated isolates were < or =0.03 for ampicillin; 0.25 for ceftiofur; 0.5 for oxytetracycline; 8 for gentamicin; 64 for spectinomycin; 0.5/9.5 for the combination trimethoprim-sulfonamides; 4 for erythromycin; 8 for tilmicosin; 1 for florfenicol and 0.125 for enrofloxacin.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Infective Agents / pharmacology
  • Antineoplastic Agents / pharmacology
  • Cattle
  • Cattle Diseases / microbiology*
  • DNA Primers / chemistry
  • DNA, Intergenic / genetics
  • Microbial Sensitivity Tests / veterinary
  • Moraxella / classification
  • Moraxella / drug effects
  • Moraxella / genetics*
  • Moraxella / isolation & purification
  • Moraxellaceae Infections / microbiology
  • Moraxellaceae Infections / veterinary*
  • Polymerase Chain Reaction / methods
  • Polymerase Chain Reaction / veterinary*
  • Polymorphism, Genetic / genetics
  • Respiratory Tract Infections / microbiology
  • Respiratory Tract Infections / veterinary*
  • Species Specificity

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • DNA Primers
  • DNA, Intergenic