Primary adrenal natural killer/T-cell nasal type lymphoma: first case report in adults

Am J Hematol. 2007 Apr;82(4):299-303. doi: 10.1002/ajh.20811.

Abstract

We report the first case of a primary adrenal natural killer (NK)/T-cell nasal type lymphoma in adults. The patient presented with an enlarging left adrenal mass and the initial concern was for adrenocortical carcinoma. Surgical resection revealed NK/T-cell lymphoma. Rapid recurrence in the contralateral adrenal gland was treated with a single cycle of chemotherapy before he died due to infectious complications and progressive disease. This case demonstrates the aggressive presentation of a novel subset of primary adrenal lymphoma that should be considered in the differential diagnosis of a rapidly enlarging adrenal mass.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / diagnosis
  • Adrenal Gland Neoplasms / pathology*
  • Adult
  • Disease Progression
  • Fatal Outcome
  • Humans
  • Immunohistochemistry
  • Killer Cells, Natural / pathology*
  • Lymphocyte Subsets / pathology*
  • Lymphoma, T-Cell / diagnosis
  • Lymphoma, T-Cell / pathology*
  • Male
  • RNA, Viral

Substances

  • Epstein-Barr virus encoded RNA 1
  • RNA, Viral