Proteasomal regulation of cardiac hypertrophy: is demolition necessary for building?

Circulation. 2006 Oct 24;114(17):1796-8. doi: 10.1161/CIRCULATIONAHA.106.656744.
No abstract available

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adaptation, Physiological
  • Animals
  • Aorta, Thoracic
  • Apoptosis / drug effects
  • Blood Pressure
  • Compliance
  • Disease Models, Animal
  • Dogs
  • Endoplasmic Reticulum / metabolism
  • Eukaryotic Initiation Factor-2 / metabolism
  • Humans
  • Hypertrophy, Left Ventricular / metabolism*
  • Ligation
  • Mice
  • Muscle Proteins / metabolism
  • Myocytes, Cardiac / drug effects
  • Myocytes, Cardiac / enzymology
  • Myocytes, Cardiac / pathology
  • Oligopeptides / pharmacology
  • Protease Inhibitors / pharmacology
  • Proteasome Endopeptidase Complex / physiology*
  • Proteasome Inhibitors
  • Protein Folding
  • Stress, Physiological / metabolism
  • Ubiquitin / metabolism
  • Vascular Resistance
  • Ventricular Remodeling / physiology*

Substances

  • Eukaryotic Initiation Factor-2
  • Muscle Proteins
  • Oligopeptides
  • Protease Inhibitors
  • Proteasome Inhibitors
  • Ubiquitin
  • Proteasome Endopeptidase Complex
  • epoxomicin