Abstract
We analyzed the configuration of the CARMA1 gene, encoding a protein that closely interacts with BCL10 and MALT1, in a series of 120 extranodal marginal zone B-cell lymphomas of MALT-type and 35 diffuse large B-cell lymphomas. Our study suggests that CARMA1 is not targeted by chromosomal translocations in these lymphoma entities.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Apoptosis Regulatory Proteins / genetics*
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CARD Signaling Adaptor Proteins / genetics*
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Guanylate Cyclase / genetics*
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Humans
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Lymphoma, B-Cell / genetics
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Lymphoma, B-Cell, Marginal Zone / genetics*
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Lymphoma, Large B-Cell, Diffuse / genetics*
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Translocation, Genetic / genetics*
Substances
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Apoptosis Regulatory Proteins
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CARD Signaling Adaptor Proteins
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CARD11 protein, human
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Guanylate Cyclase