SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry

Adv Exp Med Biol. 2006:581:335-8. doi: 10.1007/978-0-387-33012-9_60.
No abstract available

MeSH terms

  • Angiotensin-Converting Enzyme 2
  • Cathepsin L
  • Cathepsins / chemistry
  • Cathepsins / physiology*
  • Cell Line
  • Coronavirus / pathogenicity*
  • Cysteine Endopeptidases / chemistry
  • Humans
  • Membrane Fusion*
  • Membrane Glycoproteins / physiology*
  • Peptidyl-Dipeptidase A / physiology
  • Severe acute respiratory syndrome-related coronavirus / pathogenicity*
  • Spike Glycoprotein, Coronavirus
  • Viral Envelope Proteins / chemistry
  • Viral Envelope Proteins / physiology*

Substances

  • Membrane Glycoproteins
  • Spike Glycoprotein, Coronavirus
  • Viral Envelope Proteins
  • Cathepsins
  • Peptidyl-Dipeptidase A
  • ACE2 protein, human
  • Angiotensin-Converting Enzyme 2
  • Cysteine Endopeptidases
  • CTSL protein, human
  • Cathepsin L