Prospective aetiological study of diaper dermatitis in the elderly

Br J Dermatol. 2006 Nov;155(5):941-6. doi: 10.1111/j.1365-2133.2006.07423.x.

Abstract

Background: The different causes of diaper dermatitis (DD) in the elderly are not well known and the treatment is often empirical.

Objectives: To determine the causes of DD in the elderly and to evaluate the efficacy of antifungal treatments in this indication.

Methods: Consecutive patients presenting with DD were included. Clinical evaluation, skin swabs for bacterial and mycological cultures, patch testing and skin biopsy were performed at inclusion. This was followed by 1 month of topical antifungal cream and, if needed, by oral fluconazole for the second month.

Results: Forty-six patients were included (mean age 85 years). Causes of DD were established for 38 patients: 24 had candidiasis (63%), six irritant dermatitis (16%), four eczema (11%) and four psoriasis (11%). After 2 months of treatment, 27 of 37 (73%) patients were cured and five of 37 were improved.

Conclusions: Mycoses and irritant dermatitis are the main causes of DD in the elderly, and emollient skin care and topical antifungal treatment can be considered a first-line therapy for this indication.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antifungal Agents / therapeutic use
  • Candidiasis, Cutaneous / diagnosis
  • Candidiasis, Cutaneous / drug therapy
  • Candidiasis, Cutaneous / etiology
  • Dermatitis, Irritant / diagnosis
  • Dermatitis, Irritant / etiology
  • Diaper Rash / drug therapy
  • Diaper Rash / etiology*
  • Diaper Rash / microbiology
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Psoriasis / diagnosis
  • Psoriasis / etiology
  • Treatment Outcome

Substances

  • Antifungal Agents