Clinical features associated with impulse control disorders in Parkinson disease

Neurology. 2006 Oct 10;67(7):1258-61. doi: 10.1212/01.wnl.0000238401.76928.45.

Abstract

In patients with Parkinson disease (PD), impulse control disorders (ICDs) such as hypersexuality and pathologic gambling and shopping can be devastating complications of antiparkinsonian treatment. To improve their detection, we investigated clinical features associated with ICDs. Subjects were participants in a longitudinal study of PD. ICDs were associated with use of dopamine agonists and depressed mood, disinhibition, irritability, and appetite disturbance.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Case-Control Studies
  • Clinical Trials as Topic
  • Comorbidity
  • Disruptive, Impulse Control, and Conduct Disorders / diagnosis*
  • Disruptive, Impulse Control, and Conduct Disorders / epidemiology*
  • Dopamine Agonists / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / diagnosis*
  • Obsessive-Compulsive Disorder / epidemiology*
  • Parkinson Disease / diagnosis
  • Parkinson Disease / drug therapy
  • Parkinson Disease / epidemiology*
  • Prevalence
  • Risk Assessment / methods*
  • Risk Factors
  • United Kingdom / epidemiology

Substances

  • Dopamine Agonists