Controlled Support MEG imaging

Neuroimage. 2006 Nov 15;33(3):878-85. doi: 10.1016/j.neuroimage.2006.07.023. Epub 2006 Sep 15.

Abstract

In this paper, we present a novel approach to imaging sparse and focal neural current sources from MEG (magnetoencephalography) data. Using the framework of Tikhonov regularization theory, we introduce a new stabilizer that uses the concept of controlled support to incorporate a priori assumptions about the area occupied by focal sources. The paper discusses the underlying Tikhonov theory and its relationship to a Bayesian formulation which in turn allows us to interpret and better understand other related algorithms.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Bayes Theorem
  • Brain / anatomy & histology
  • Computer Simulation
  • Humans
  • Image Processing, Computer-Assisted / statistics & numerical data*
  • Magnetoencephalography / methods*
  • Magnetoencephalography / statistics & numerical data*
  • Monte Carlo Method
  • Reproducibility of Results