Abstract
Supratentorial primitive neuro-ectodermal tumors (PNET) in adults are very rare. Extraneural metastasis are unusual and the optimal palliative chemotherapy regimen is not established. We present a 26-year-old patient with local recurrence and distant metastasis of supratentorial PNET successfully treated with intensive induction chemotherapy and maintenance temozolomide.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bone Marrow Neoplasms / drug therapy
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Bone Marrow Neoplasms / secondary*
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Cyclophosphamide / administration & dosage
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Dacarbazine / administration & dosage
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Dacarbazine / analogs & derivatives
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Doxorubicin / administration & dosage
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Humans
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Liver Neoplasms / drug therapy
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Liver Neoplasms / secondary*
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Male
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Methotrexate / administration & dosage
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Neoplasm Recurrence, Local / drug therapy*
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Neoplasm Recurrence, Local / surgery
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Neuroectodermal Tumors, Primitive / drug therapy
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Neuroectodermal Tumors, Primitive / secondary*
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Prednisone / administration & dosage
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Remission Induction
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Supratentorial Neoplasms / drug therapy
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Supratentorial Neoplasms / pathology*
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Supratentorial Neoplasms / surgery
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Temozolomide
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Treatment Outcome
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Vincristine / administration & dosage
Substances
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Vincristine
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Dacarbazine
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Doxorubicin
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Cyclophosphamide
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Prednisone
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Temozolomide
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Methotrexate