Abstract
The influence of cellular differentiation on colony-stimulating factor gene expression was examined in myogenically and adipogenically determined cell lines derived from 5-azacytidine-treated C3H10T1/2 C18 (10T1/2) mouse embryo fibroblasts. These studies demonstrate that colony-stimulating factor gene expression can be modulated by myogenic and adipogenic determination and terminal differentiation.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adipose Tissue / cytology*
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Animals
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Azacitidine / pharmacology
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Cell Differentiation* / drug effects
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Cell Division / drug effects
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Cell Line
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Clone Cells
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Colony-Stimulating Factors / genetics*
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Gene Expression*
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Granulocyte Colony-Stimulating Factor
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Granulocyte-Macrophage Colony-Stimulating Factor
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Growth Substances / genetics
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Kinetics
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Macrophage Colony-Stimulating Factor
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Mice
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Muscles / cytology*
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Transcription, Genetic
Substances
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Colony-Stimulating Factors
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Growth Substances
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Granulocyte Colony-Stimulating Factor
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Macrophage Colony-Stimulating Factor
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Granulocyte-Macrophage Colony-Stimulating Factor
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Azacitidine