Fecal viral load and norovirus-associated gastroenteritis

Emerg Infect Dis. 2006 Aug;12(8):1278-80. doi: 10.3201/eid1208.060081.

Abstract

We report the median cDNA viral load of norovirus genogroup II is >100-fold higher than that of genogroup I in the fecal specimens of patients with norovirus-associated gastroenteritis. We speculate that increased cDNA viral load accounts for the higher transmissibility of genogroup II strains through the fecal-oral route.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Caliciviridae Infections / virology
  • Child
  • Child, Preschool
  • DNA, Complementary / analysis
  • DNA, Viral / analysis
  • Feces / virology*
  • Female
  • Gastroenteritis / virology*
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Norovirus / classification
  • Norovirus / genetics
  • Norovirus / isolation & purification*
  • Viral Load

Substances

  • DNA, Complementary
  • DNA, Viral