Abstract
The Genotype MTBDR assay was tested for its capability to detect rifampicin (RMP) and isoniazid (INH) resistance (r) and susceptibility (s) directly from 42 smear-positive sputum specimens (15 RMPr/INHr, 2 RMPs/INHr and 25 RMPs/INHs Mycobacterium tuberculosis complex strains). The concordance between the MTBDR assay and conventional drug susceptibility testing was 100%.
MeSH terms
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Antitubercular Agents / pharmacology*
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DNA, Bacterial / genetics*
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Drug Resistance, Bacterial
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Genotype
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Humans
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Isoniazid / pharmacology*
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Microbial Sensitivity Tests / methods
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Mycobacterium tuberculosis / drug effects*
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Mycobacterium tuberculosis / genetics*
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Rifampin / pharmacology*
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Sputum / microbiology*
Substances
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Antitubercular Agents
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DNA, Bacterial
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Isoniazid
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Rifampin