A pharmacogenomic study of atorvastatin effects on eNOS activity: do "statins" modulate blood nitrite levels and intravascular oxidant stress in susceptible individuals?

Free Radic Biol Med. 2006 Oct 1;41(7):1041-3. doi: 10.1016/j.freeradbiomed.2006.05.034. Epub 2006 Jun 10.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Atorvastatin
  • Heptanoic Acids / pharmacology*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology
  • Nitric Oxide Synthase Type III / metabolism*
  • Nitrites / blood*
  • Oxidative Stress / drug effects*
  • Pyrroles / pharmacology*

Substances

  • Heptanoic Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Nitrites
  • Pyrroles
  • Atorvastatin
  • NOS3 protein, human
  • Nitric Oxide Synthase Type III