As the population rapidly ages, osteoporosis has been a serious problem. The incidence of hip fracture, which is the most serious complication for osteoporosis, is increasing and over 1,000 thousands per year, while, the incidence of vertebral fracture is still five times more than that of hip fracture. The incidence of hip fracture, vertebral fracture and proximal humeral fracture increases with ages, however, that of distal radial fracture does not. Fracture, especially hip fracture and vertebral fracture, is associated with mortality. Thus, prevention for fracture in the elderly is very important issue.