Abstract
Itch is an important, but underestimated symptom in psoriasis. Many therapies are available for pruritus; however, few are effective for psoriatic itch. Antipruritic therapies that are potentially effective in psoriasis include coal tar products, topical corticosteroids, topical salicylates, menthol and pramoxine, capsaicin, phototherapy, vitamin D analogs, topical immunomodulators, methotrexate, oral mirtazapine, and biologics. Using these therapies can benefit psoriasis patients in the outpatient clinical setting.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Administration, Cutaneous
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Anti-Inflammatory Agents / therapeutic use
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Antipruritics / therapeutic use
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Capsaicin / therapeutic use
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Coal Tar / therapeutic use
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Emollients / therapeutic use
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Histamine H1 Antagonists / therapeutic use
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Humans
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Immunologic Factors / therapeutic use
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Immunosuppressive Agents / therapeutic use
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Keratolytic Agents / therapeutic use
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Methotrexate / therapeutic use
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Mianserin / analogs & derivatives
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Mianserin / therapeutic use
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Mirtazapine
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Morpholines / therapeutic use
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Phototherapy
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Pruritus / etiology*
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Pruritus / psychology
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Pruritus / therapy*
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Psoriasis / complications*
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Quality of Life
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Salicylates / therapeutic use
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Skin Care / methods
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Vitamin D / analogs & derivatives
Substances
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Anti-Inflammatory Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Antipruritics
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Emollients
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Histamine H1 Antagonists
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Immunologic Factors
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Immunosuppressive Agents
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Keratolytic Agents
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Morpholines
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Salicylates
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pramoxine
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Vitamin D
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Mianserin
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Coal Tar
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Mirtazapine
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Capsaicin
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Methotrexate