Voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis clinical trial

J Clin Microbiol. 2006 Jul;44(7):2579-80. doi: 10.1128/JCM.00818-06.

Abstract

In this study, the voriconazole susceptibilities of dermatophyte isolates obtained from a worldwide tinea capitis trial were compared to their susceptibilities to fluconazole and griseofulvin. The MIC ranges of voriconazole, fluconazole, and griseofulvin, were 0.002 to 0.06 microg/ml, 0.25 to 32 microg/ml, and 0.125 to 2.0 microg/ml, respectively.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Arthrodermataceae / drug effects*
  • Arthrodermataceae / isolation & purification
  • Clinical Trials as Topic
  • Fluconazole / pharmacology
  • Griseofulvin / pharmacology
  • Humans
  • Microbial Sensitivity Tests
  • Pyrimidines / pharmacology*
  • Tinea Capitis / microbiology*
  • Triazoles / pharmacology*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Griseofulvin
  • Fluconazole
  • Voriconazole