Cognitive control impairments in traumatic brain injury

J Clin Exp Neuropsychol. 2006 Aug;28(6):968-86. doi: 10.1080/13803390600646860.

Abstract

The componential nature of impaired cognitive control following traumatic brain injury (TBI) remains uncertain. We examined regulative and evaluative components of cognitive control in mild and moderate-to-severe (M/S) TBI patients and demographically-matched comparison participants using the AX-CPT task. We also examined relationships of cognitive control impairment to ratings of cognitive, behavioral, and affective symptomatology on the Dysexecutive Questionnaire (DEX). Results revealed that M/S, but not mild TBI patients showed deficits in context-processing and post-error strategic adjustments -- extent of impairments correlated with TBI-related symptomatology. Thus, patients with M/S TBI evidence cognitive control dysfunction in the processing and active maintenance of context representations.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Brain Injuries / physiopathology*
  • Cognition Disorders / physiopathology*
  • Demography
  • Female
  • Humans
  • Male
  • Neuropsychological Tests / statistics & numerical data
  • Severity of Illness Index
  • Surveys and Questionnaires